Research Studies on the effects of Hemp Oil on Epilepsy

 let’s look at how Hemp Oil may help …

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 Research articles and Studies show how Hemp Oil may help with Epilepsy

Leinow, Leonard; Birnbaum, Juliana. CBD: A Patient’s Guide to Medicinal Cannabis–Healing without the High (p. 163). North Atlantic Books

CBD oil has been shown to dramatically stop and slow seizures in its tracks

“Out of all of the many medicinal uses of CBD, using it for seizure control has shown some of the most spectacular and well-publicized results. It is dramatic and potentially life threatening when a person, especially an infant or child, has a grand mal epileptic seizure. After administration of the proper dose of medical-grade, plant-based CBD medicine, for many patients seizures are greatly reduced and in some cases stop altogether. Studies vary on the efficacy rate (see more information later in this section), but many experience a reduction in frequency, intensity, and duration of seizures.
CBD shows the most promising results among the cannabinoids studied for seizure control, but some types of seizures appear to respond better to higher ratios of THC. Research indicates that the effects of CB1 receptor signaling on seizures are related to the way in which specific cannabinoids interact with the receptor, as either agonist or antagonist. 403 In a 2015 open-label study of 162 pediatric epilepsy patients at centers across the United States, researchers administered CBD at a rate of 4– 10 mg/ lb per day and up-titrated until intolerance or to a maximum.
In a study presented in 2016 of 201 children with epilepsy using high-CBD oils, with doses recommended by Dr. Bonni Goldstein, 68 percent of epileptic patients had greater than 50 percent improvement and 15 percent are seizure free. Over 40 percent of those studied were able to reduce or totally eliminate pharmaceutical drugs. 404 Positive side effects included improved energy, mood, and sleep; improved appetite and focus; and reduced ER visits and hospitalizations. Negative side effects included drowsiness and diarrhea.

A 2016 retrospective study of seventy-four pediatric patients in Israeli clinics found that 89 percent reported a reduction in seizure load with CBD therapy. Five patients reported aggravated seizures.”

Cannabidiol (CBD) and cognition in Epilepsy – Targeted Review

“Only recently, randomized controlled trial data in support of cannabidiol (CBD) became available resulting in its FDA approval for the treatment of seizures and epilepsy.
Available data on cannabidiol (CBD) and effects on cognition in epilepsy are presented – highlights:
Cannabidiol has anti-inflammatory, anti-oxidant, and neuroprotective properties.
In multiple animal models of epilepsy, CBD was shown to improve cognition.
Studies in humans demonstrate neutral or positive effects of CBD on cognition in epilepsy.”
Cannabidiol can induce functional brain changes important in cognition in epilepsy.”
“CBD has been shown to have additional mechanisms of action (MOA) that result in neuroprotective, anti-inflammatory, anti-oxidant, and neurogenesis effects. These additional MOAs suggest that the use of CBD could lead to other actions including positive effects on cognition that may be independent of seizure control.”

Epilepsy & Behavior – Science Direct Volume 124, Nov 2021, 108316 sciencedirect.com/science/article/abs/pii/S1525505021005771

Chronic cannabidiol (CBD) administration induces anticonvulsant and antiepileptogenic effects in a genetic model of epilepsy

Cannabidiol (CBD) administration induced anticonvulsant and antiepileptogeniceffects.
Highlights: CBD prevented chronic neuronal hyperactivity induced by chronic seizures.

CBD attenuated brainstem seizures and prevented the development of limbic seizures

Chronic CBD prevented neuroplastic changes in CB1R induced by chronic seizures.

Neuroethological analysis supports chronic CBD protective effects for epilepsy

 The neuroethological analysis provided details about CBD’s protective effects against brainstem and limbic seizures associated with FosB expression. Our results strongly suggest chronic CBD anticonvulsant and antiepileptogeniceffects associated with reduced chronic neuronal activity and modulation of CB1R expression. We also support the chronic use of CBD for epilepsies treatments.

Epilepsy & Behavior – Science Direct Volume 119, June 2021, 107962 www.sciencedirect.com/science/article/abs/pii/S1525505021001967

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~ Calms the central nervous system to naturally reduce chronic pain

~ Works with your own natural Endocannabinoid System

~ Does NOT contain THC that could make someone high

~ Strengthens your immune and digestive system

~ Has therapeutic potential in almost all diseases affecting humans

~ Can help animals much the same way

~ Contains cannabinoids that are also produced naturally in breast milk

~ Works to bring ALL systems of the body into homeostasis

~ Naturally allows your body to heal from the ROOT of the problem


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